发明名称 |
Methods for producing chiral aldehydes |
摘要 |
The present invention relates to methods for producing chiral aldehydes by the enantioselective hydroformylation of prochiral substrates with the aid of a catalyst consisting of a transition metal and a chiral ligand, characterized in that said chiral ligand is a compound of general formula 1wherein the rings R7-R10 drawn with dotted lines are optional and one or more of rings R1-R6 or R7-R10 are substituted with one or more independently selected substituents of general formula -(CH2)x(CF2)yF(x=0-5; y=1-12) or their branched isomers. In particular, the invention relates to the conducting of the mentioned methods in compressed (liquid or supercritical) carbon dioxide as the reaction medium.
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申请公布号 |
US6399834(B1) |
申请公布日期 |
2002.06.04 |
申请号 |
US20010831925 |
申请日期 |
2001.05.15 |
申请人 |
STUDIENGESELLSCHAFT KOHLE MBH |
发明人 |
LEITNER WALTER;KAINZ SABINE;KOCH DANIEL;FRANCIO GIANCARLO |
分类号 |
B01J31/20;C07B53/00;C07B61/00;C07C45/50;C07C47/228;C07C47/24;(IPC1-7):C07C45/50 |
主分类号 |
B01J31/20 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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