发明名称 |
Signal generating oligonucleotide-based biosensor |
摘要 |
The present invention relates to oligonucleotide-based biosensors and a general method for their production and use. Specifically, the invention describes a novel signal-generating ligand complex comprising the combination of two or more aptamers linked together by a polymeric linker and further comprising a signaling system that provides a detectable signal upon binding of the signal-generating ligand complex to its target analyte.
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申请公布号 |
US6399302(B1) |
申请公布日期 |
2002.06.04 |
申请号 |
US20000529870 |
申请日期 |
2000.04.19 |
申请人 |
UNIVERSITY OF VIRGINIA PATENT FOUNDATION |
发明人 |
LANNIGAN DEBORAH A.;MACARA IAN G. |
分类号 |
C07H21/02;C07H21/04;C12M1/34;C12N15/11;C12Q1/68;G01N33/532;G01N33/542;(IPC1-7):C12Q1/68 |
主分类号 |
C07H21/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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