发明名称 |
Dibenzosberanyl piperazine derivatives and drug-resistance overcoming agents containing the derivatives |
摘要 |
Dibenzosuberanyl piperazine derivatives represented by the following formula (I): <CHEM> wherein R represents an aliphatic hydrocarbon group, which may contain one or more heteroatom-containing substituent groups and may preferably contain 2 to 30 carbon atoms, and physiologically acceptable salts thereof; and medicinal compositions containing these dibenzosuberanyl piperazine derivatives and/or physiologically acceptable salts thereof. These compounds show effectiveness in allowing resistance-acquired causes of diseases to restore sensitivity to drug, that is, a resistance overcoming effect. |
申请公布号 |
AU1433102(A) |
申请公布日期 |
2002.06.03 |
申请号 |
AU20020014331 |
申请日期 |
2001.11.20 |
申请人 |
POLA CHEMICAL INDUSTRIES INC.;TSUTOMU TAKEUCHI;HIROAKI TAKAYANAGI |
发明人 |
TSUTOMU TAKEUCHI;HIROAKI TAKAYANAGI;SEIKI KOBAYASHI;YUMIKO OSA;YUMIKO SUZUKI;YOKO SATO;MASAKAZU SAKAGUCHI;YOSHIYUKI MIYATA |
分类号 |
A61K31/495;A61P33/06;A61P43/00;C07D295/084;C07D295/088 |
主分类号 |
A61K31/495 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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