VON WILLEBRAND FACTOR (vWF) CLEAVING PROTEASE POLYPEPTIDE, NUCLEIC ACID ENCODING THE POLYPEPTIDE AND USE OF POLYPEPTIDE

摘要

The invention relates to a vWF cleaving protease (vWF-cp) polypeptide, a nucleic acid molecule encoding the amino acid sequence of a vWF-cp polypeptide and a composition comprising the polypeptide. The invention also relates to the use of the vWF cleaving protease polypeptide for production of vWF cleaving protease polypeptide binding molecules and for production of a preparation for prophylaxis and therapy of thrombosis and thromboembolic disease.