发明名称 |
Genes that regulate hematopoietic blood forming stem cells and uses thereof |
摘要 |
The present invention provides an isolated nucleic acid derived from an isolated hematopoietic stem cell. The present invention additionally provides an isolated hematopoietic stem cell specific protein or a portion thereof encoded by the provided nucleic acid. In addition, the present invention provides a method for generating a stem cell/progenitor cell from a primitive hematopoietic cell. Also, the present invention farther provides a method for identifying the presence in a sample of a compound that modulates hematopoietic stem cell activity. The present invention additionally provides a molecularly defined primitive hematopoietic stem cell. Finally, the present invention provides a method of ex vivo expansion of hematopoietic stem cells.
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申请公布号 |
US2002064855(A1) |
申请公布日期 |
2002.05.30 |
申请号 |
US20010789919 |
申请日期 |
2001.02.21 |
申请人 |
LEMISCHKA IHOR;MOORE KATERI |
发明人 |
LEMISCHKA IHOR;MOORE KATERI |
分类号 |
A61K38/00;C07K14/47;(IPC1-7):C12N9/02;C12N9/64;C07H21/04;C12P21/02;C12N5/08 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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