MODIFIER OF ORGANELLE METALBOLISM

摘要

The invention relates to a nucleic acid molecule encoding a polypeptide contributing to membrane stability and/or function of organelles, wherein said nucleic acid molecule (a) hybridizes under herein defined conditions to the complementary strand of a nucleic acid molecule encoding the amino acid sequence disclosed herein; (b) hybridizes under herein defined conditions to the complementary strad of a nucleic acid molecule as depicted herein; (c) it is degenerate with respect to the nucleic acid molecule of (a); (d) encodes a polypeptide which comprises at least one, preferably at least two, more preferably at least three, more preferably at least four, more preferably at least five and most preferably six amino acid sequences being part of the polypeptide contributing to membrane stability and/or function of organelles and comprising putative transmembrane region; (e) encodes a polypeptide which is at least 85%, preferably at least 90%, more preferably at least 95%, more preferabliy at least 98% and up to 99,6% identical to an amino acid sequence representing the above described polypeptide; (g) encodes a polypeptide which is at least 35%, preferably at least 50%, more preferably at least 60%, more preferably at least 70% more preferably at least 80%, more proferably at least 99%, most preferably at least 95% and most preferably at least 99% identical to the amino acid sequence as disclosed herein; (h) differs from the nucleic acid molecule of (a) to (g) by mutation and wherein said mutation causes an alteration, deletion, duplication or premature stop in the encoded polypeptide; or (i) has a sequence as disclosed herein.