发明名称 |
Screen for compounds with affinity for nucleic acids |
摘要 |
The present invention provides methods for high-throughput screening for bioactive compounds, in particular those that bind to RNA sequences involved in the pathogenesis of disease or in regulation of a physiological function. The methods involve measuring the conformation of an RNA target in the presence and absence of test ligands, and identifying as a ligand any test ligand that causes a measurable change in target RNA conformation.
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申请公布号 |
US2002064793(A1) |
申请公布日期 |
2002.05.30 |
申请号 |
US20010962432 |
申请日期 |
2001.09.24 |
申请人 |
ANADYS PHARMACEUTICALS, INC. |
发明人 |
ARENAS JAIME E.;LILLIE JAMES W.;PAKULA ANDREW |
分类号 |
G01N33/566;C12N15/09;C12Q1/68;(IPC1-7):C12Q1/68 |
主分类号 |
G01N33/566 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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