SUBSTITUTED POLYCYCLIC ARYL AND HETEROARYL PYRIDINES USEFUL FOR SELECTIVE INHIBITION OF THE COAGULATION CASCADE
摘要
The present invention relates to compounds, and prodrugs thereof, compositio n and methods useful for preventing and treating thrombotic conditions in mammals. The compounds of the present invention, and prodrugs thereof, selectively inhibit certain proteases of the coagulation cascade.
申请公布号
CA2430037(A1)
申请公布日期
2002.05.30
申请号
CA20012430037
申请日期
2001.11.20
申请人
PHARMACIA CORPORATION
发明人
HUANG, WEI;HUANG, HORNG-CHIH;HAYES, MICHAEL J.;GARLAND, DANNY J.;CASE, BRENDA;SOUTH, MICHAEL S.;WEBBER, RONALD K.;JONES, DARIN E.;NEUMANN, WILLIAM L.;PARLOW, JOHN J.;REITZ, DAVID B.;RUEPPEL, MELVIN L.