摘要 |
<p>A diagnosis kit for estimating the advance stage of a disease in which HIV-1 participates and/or the efficacy of an anti-HIV-1 therapy by using the content of an HIV RNA-DNA hybrid in the sample as an indication, which contains at least a pair of primers consisting of a downstream primer having a sequence complementary to a part of the base sequence of the RNA constituting the HIV-1 RNA-DNA hybrid and an upstream primer having a sequence complementary to a part of the base sequence of the DNA constituting the HIV-1 RNA-DNA hybrid, and a restriction enzyme capable of cleaving a double-stranded DNA containing the same base sequence as the DNA extended by the above-described primer pair at any position in the above-described base sequence.</p> |