COMBINATION COMPRISING AN AGENT DECREASING VEGF ACTIVITY AND AN AGENT DECREASING EGF ACTIVITY
摘要
The invention relates to a combination which comprises a first active ingredient which is a vasculostatic compound and a second active ingredient which decreases the activity of the epidermal growth factor (EGF), in particular, for the delay of progression or treatment of a disease associated with deregulated angiogenesis, especially a proliferative disease; a pharmaceutical composition comprising such a combination; a commercial package comprising such a combination as a combined preparation; and to a method of treatment of a warm-blooded animal, especially a human.
申请公布号
WO0241882(A2)
申请公布日期
2002.05.30
申请号
WO2001EP13441
申请日期
2001.11.20
申请人
NOVARTIS AG;NOVARTIS-ERFINDUNGEN VERWALTUNGSGESELLSCHAFT M.B.H.;WOOD, JEANETTE, MARJORIE;BRANDT, RALF;BOLD, GUIDO;TRAXLER, PETER
发明人
WOOD, JEANETTE, MARJORIE;BRANDT, RALF;BOLD, GUIDO;TRAXLER, PETER