发明名称 COMBINATION COMPRISING AN AGENT DECREASING VEGF ACTIVITY AND AN AGENT DECREASING EGF ACTIVITY
摘要 The invention relates to a combination which comprises a first active ingredient which is a vasculostatic compound and a second active ingredient which decreases the activity of the epidermal growth factor (EGF), in particular, for the delay of progression or treatment of a disease associated with deregulated angiogenesis, especially a proliferative disease; a pharmaceutical composition comprising such a combination; a commercial package comprising such a combination as a combined preparation; and to a method of treatment of a warm-blooded animal, especially a human.
申请公布号 WO0241882(A2) 申请公布日期 2002.05.30
申请号 WO2001EP13441 申请日期 2001.11.20
申请人 NOVARTIS AG;NOVARTIS-ERFINDUNGEN VERWALTUNGSGESELLSCHAFT M.B.H.;WOOD, JEANETTE, MARJORIE;BRANDT, RALF;BOLD, GUIDO;TRAXLER, PETER 发明人 WOOD, JEANETTE, MARJORIE;BRANDT, RALF;BOLD, GUIDO;TRAXLER, PETER
分类号 A61K31/404;A61K31/505;A61K31/519;A61K31/5375;A61K31/70;A61K45/06;A61P1/16;A61P3/10;A61P9/10;A61P9/12;A61P13/12;A61P25/28;A61P27/02;A61P29/00;A61P35/00;A61P35/02;A61P35/04;A61P37/06;A61P43/00 主分类号 A61K31/404
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