| 发明名称 |
Alpha-and beta- substituted trifluoromethyl ketones as phospholipase inhibitors |
| 摘要 |
Inhibitors of the cytosolic phospholipase A2 enzymes are provided which are of use in controlling a wide variety of inflammatory diseases. The inhibitors of the present invention have the general formula where X, Z, R1, R2, R3, R4, Ra and Rb are as defined in the specification.
|
| 申请公布号 |
US2002065246(A1) |
申请公布日期 |
2002.05.30 |
| 申请号 |
US20010816574 |
申请日期 |
2001.03.23 |
| 申请人 |
BANVILLE JACQUES;MARINIER ANNE;GAI YONGHUA;PLAMONDON SERGE;ROY STEPHAN;BALASUBRAMANIAN NEELAKANTAN |
发明人 |
BANVILLE JACQUES;MARINIER ANNE;GAI YONGHUA;PLAMONDON SERGE;ROY STEPHAN;BALASUBRAMANIAN NEELAKANTAN |
| 分类号 |
A61K31/192;A61K31/216;A61K31/277;A61K31/695;C07C217/22;C07C317/18;C07C323/12;C07C323/52;C07D303/48;(IPC1-7):A61K31/695;C07F7/04;C07F9/141 |
主分类号 |
A61K31/192 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
