| 摘要 |
<p>The present invention is directed to neutron capture agents, such as a molecule comprising Boron-10 or Gadolinium-157, for the treatment, prophylaxis and/or diagnosis of a proliferative disorder via a direct or indirect attachment to a compound that binds to a transport protein for vitamin B12, i.e. transcobalamin I, II or III, or intrinsic factor, (the TC- or IF-binding carrier). Subsequent initiation of neutron capture therapy will selectively destroy abnormally proliferating cells.</p> |
