| 发明名称 |
METHOD FOR PRODUCING A HETEROLOGOUS SECRETED PROTEIN FROM CHINESE HAMSTER OVARY CELLS GROWN ON MICROCARRIERS |
| 摘要 |
<p>The present invention relates to a method for producing a heterologous secreted protein from transformed CHO cells grown on microcarriers in a serum-free cell culture medium. This method avoids a production lag phase when switching from a serum-containing to a serum-free environment, a problem observed in the mammalian adherent cell culture production of secreted proteins.</p> |
| 申请公布号 |
EP1208192(A1) |
申请公布日期 |
2002.05.29 |
| 申请号 |
EP20000959701 |
申请日期 |
2000.09.01 |
| 申请人 |
APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. |
发明人 |
CUNNINGHAM, MARK;IHEY, TOM |
| 分类号 |
C12N15/09;C07K14/715;C12N5/00;C12N5/10;C12N15/12;C12P21/02;C12P21/04;C12R1/91;(IPC1-7):C12N5/06 |
主分类号 |
C12N15/09 |
| 代理机构 |
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