发明名称 NOVEL IMIDAZOLE DERIVATIVES, PRODUCTION METHOD THEREOF AND USE THEREOF
摘要 The present invention provides a compound having a steroid C17,20-lyase- inhibitory activity and useful for the therapy and prophylaxis of tumor such as prostatism, breast cancer and the like, and a method for efficiently separating an optically active compound of this compound from a mixture of optical isomers thereof, a compound of the formula:wherein each symbol is as defined in the specification, a salt thereof or a prodrug thereof, and a method for obtaining an optically active compound by optically resolving a mixture of optical isomers by the use of a resolving agent such as tartranilic acid and the like.
申请公布号 CA2429133(A1) 申请公布日期 2002.05.23
申请号 CA20012429133 申请日期 2001.11.16
申请人 TAKEDA CHEMICAL INDUSTRIES, LTD. 发明人 OJIDA, AKIO;TASAKA, AKIHIRO;AOKI, ISAO;ADACHI, MARI;HITAKA, TAKENORI;KUSAKA, MASAMI;MATSUNAGA, NOBUYUKI
分类号 C07D233/62;A61K31/165;A61K31/4174;A61K31/4188;A61K31/437;A61K45/00;A61P5/28;A61P35/00;A61P43/00;C07D233/54;C07D471/04;C07D487/04;(IPC1-7):C07D487/04;C07D209/00;C07D221/00;C07D235/00;A61K31/418 主分类号 C07D233/62
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