发明名称 |
NOVEL IMIDAZOLE DERIVATIVES, PRODUCTION METHOD THEREOF AND USE THEREOF |
摘要 |
The present invention provides a compound having a steroid C17,20-lyase- inhibitory activity and useful for the therapy and prophylaxis of tumor such as prostatism, breast cancer and the like, and a method for efficiently separating an optically active compound of this compound from a mixture of optical isomers thereof, a compound of the formula:wherein each symbol is as defined in the specification, a salt thereof or a prodrug thereof, and a method for obtaining an optically active compound by optically resolving a mixture of optical isomers by the use of a resolving agent such as tartranilic acid and the like.
|
申请公布号 |
CA2429133(A1) |
申请公布日期 |
2002.05.23 |
申请号 |
CA20012429133 |
申请日期 |
2001.11.16 |
申请人 |
TAKEDA CHEMICAL INDUSTRIES, LTD. |
发明人 |
OJIDA, AKIO;TASAKA, AKIHIRO;AOKI, ISAO;ADACHI, MARI;HITAKA, TAKENORI;KUSAKA, MASAMI;MATSUNAGA, NOBUYUKI |
分类号 |
C07D233/62;A61K31/165;A61K31/4174;A61K31/4188;A61K31/437;A61K45/00;A61P5/28;A61P35/00;A61P43/00;C07D233/54;C07D471/04;C07D487/04;(IPC1-7):C07D487/04;C07D209/00;C07D221/00;C07D235/00;A61K31/418 |
主分类号 |
C07D233/62 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|