发明名称 NOVEL USE OF CERTAIN INSULIN SENSITIZERS OR PPAR-GAMMA AGONISTS
摘要 A use of certain insulin sensitiser or a PPAR gamma agonist such as a compound of formula (I) or a tautomeric form thereof and/or a pharmaceutically acceptable salt thereof, and/or a pharmaceutically acceptable solvate thereof, wherein: A<1> represents a substituted or unsubstituted aromatic heterocyclyl group; R<1> represents a hydrogen atom, an alkyl group, an acyl group, an aralkyl group, wherein the aryl moiety may be substituted or unsubstituted, or a substituted or unsubstituted aryl group; R<2> and R<3> each represent hydrogen, or R<2> and R<3> together represent a bond; A<2> represents a benzene ring having in total up to five substituents; and n represents an integer in the range of from 2 to 6, for the manufacture of a medicament for treatment and/or prophylaxis of diseases associated with loss of bone mass, such as osteoporosis and related osteopenic diseases, Paget's disease, hyperparathyroidism and related diseases.
申请公布号 WO0240020(A1) 申请公布日期 2002.05.23
申请号 WO2001GB05044 申请日期 2001.11.14
申请人 SMITHKLINE BEECHAM P.L.C.;BUCKINGHAM, ROBIN, EDWIN 发明人 BUCKINGHAM, ROBIN, EDWIN
分类号 C07D263/32;A61K31/421;A61K31/427;A61K31/4439;A61P5/18;A61P19/08;A61P19/10;C07D417/12;(IPC1-7):A61K31/427 主分类号 C07D263/32
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