发明名称 Dosage forms useful for modifying conditions and functions associated with hearing loss and/or tinnitus
摘要 The invention defines interdependent biofactors and biomolecules, and clinically useful formulations that are comprised of them. The active agents are demonstrated to be complementary in their physiologic functions especially as these relate to the quenching of free radicals and to the support of endothelial physiology, the reduction of hyperinsulinemia and improvements in vascular health. The active components of the invention are selected for inclusion in precise combinations specifically because they improve these various conditions and physiological functions, and by so doing reduce a variety of risks associated with hearing loss and tinnitus. The resulting enhancement of general systemic vascular health, improvement in local VIIIth nerve vascular health, modulation of conditions surrounding blood fluid dynamics, the consequences of hyperinsulinemia, and improvements in free radical defenses, all reduce the potential for cochlear hair cell death and VIIIth nerve atrophy, and the hearing loss and possible deafness that accompany them.
申请公布号 US2002061870(A1) 申请公布日期 2002.05.23
申请号 US20010765974 申请日期 2001.01.19
申请人 PEARSON DON C.;RICHARDSON KENNETH T. 发明人 PEARSON DON C.;RICHARDSON KENNETH T.
分类号 A61K9/22;A61K9/24;A61K31/28;A61K31/30;A61K31/315;A61K31/555;A61K33/30;(IPC1-7):A61K31/555;A61K31/525;A61K31/195 主分类号 A61K9/22
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