发明名称 SPECIFIC PROMOTER OF THE HUMAN VASCULAR ENDOTHELIAL CADHERIN-2 (HVE-CAD-2) GENE AND THE THERAPEUTIC USES THEREOF
摘要 The invention relates to a nucleic acid fragment which contains the regulatory sequence of the VE-Cad-2- gene, a complete or a functional active variation thereof. The invention also relates to a nucleic acid construct containing the nucleic acid fragment and a functional nucleic acid sequence or a heterological gene, a vector or a vector system, a cell or a cell line, a transgenic non-human animal, a medicament, a diagnostic, an array, a method for identifying pharmaceutically active substances, a method for identifying functionally active variants, a method for isolating endothelium cells from stem cells, a method for treatment, a method for administering a medicament, the use of the nucleic acid fragment, the nucleic acid construct, the transformed cell or cell lines of the tests and the arrays.
申请公布号 CA2429317(A1) 申请公布日期 2002.05.23
申请号 CA20012429317 申请日期 2001.11.16
申请人 CARDION AG 发明人 ZWEIGERDT, ROBERT;RUDIGER, MANFRED;MOLL, THOMAS G.
分类号 A61P9/00;C07K14/705;(IPC1-7):C12N15/85;A01K67/00;A61K48/00;C12N15/11;C12N5/16;C12Q1/68 主分类号 A61P9/00
代理机构 代理人
主权项
地址