发明名称 |
New pyridazine endothelin antagonists |
摘要 |
Compounds of formula (I), pharmaceutical formulations thereof and the use of such compounds for treating endothelin mediated diseases or conditions are described herein. The compounds of the present invention have affinity for endothelin receptors, are selective for ETA over ETB, and thus are useful in the treatment of conditions mediated by endothelin.
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申请公布号 |
US2002061889(A1) |
申请公布日期 |
2002.05.23 |
申请号 |
US20010951019 |
申请日期 |
2001.09.12 |
申请人 |
BANKS BERNARD JOSEPH;CHUBB ANTHONY LOGAN;CRITCHER DOUGLAS JAMES;ESHELBY JAMES JOHN;SCHULZ DARREN JOHN |
发明人 |
BANKS BERNARD JOSEPH;CHUBB ANTHONY LOGAN;CRITCHER DOUGLAS JAMES;ESHELBY JAMES JOHN;SCHULZ DARREN JOHN |
分类号 |
A61P9/08;A61P9/10;C07D403/04;(IPC1-7):C0743/02;A61K31/501 |
主分类号 |
A61P9/08 |
代理机构 |
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