发明名称 |
METHOD AND DEVICE FOR PRODUCING BIOLOGICAL PROSTHESES |
摘要 |
The invention relates to a method for coating biological implants with autologous cells of the recipient, according to which the cell-free allogenic or xenogenic material foreign to the body is colonized in a speed-variable pulsating cell suspension flow close to the natural conditions in the respective organ or part of the organ. The resulting cell conditioning allows a complete, fast and safe coating with cells, the formation of which comes close to the natural conditions and guarantees a trouble-free functioning and a long life of the implant. The device for carrying out the method comprises a bioreactor (2) integrated into a loop (1) and filled with the cell suspension in which the implant (8) is axially and centrally fixated in the direction of flow. The loop (1) is connected to a pump (3) that generates a pulsating flow of medium that flows through the implant (8). The inventive coating with autologous cells can also be applied to artificial prostheses.
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申请公布号 |
WO0240076(A1) |
申请公布日期 |
2002.05.23 |
申请号 |
WO2001DE03632 |
申请日期 |
2001.09.19 |
申请人 |
AUTOTISSUE GMBH;KONERTZ, WOLFGANG;DOCHMEN, PASCAL |
发明人 |
KONERTZ, WOLFGANG;DOCHMEN, PASCAL |
分类号 |
A61F2/06;A61F2/24;A61L27/38;(IPC1-7):A61L27/38 |
主分类号 |
A61F2/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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