New nucleic acid encoding plant phosphomevalonate kinase, useful for identifying modulators, potentially useful as herbicides and growth regulators

摘要

A nucleic acid (I) that encodes a plant phosphomevalonate kinase (PMVK), excluding the known fully defined partial sequences (S3-5) of 611, 728 and 571 base pairs as given in the specification, is new. Independent claims are also included for the following: (a) DNA construct (DC) comprising (I) and a heterologous promoter; (b) vector containing (I) or DC; (c) host cell containing (I), DC or the vector of (b); (d) polypeptide (II) with PMVK activity encoded by (I); (e) antibody (Ab) that binds specifically to (II); (f) preparing (I) or (II); (g) identifying compounds (A) that bind to and/or modulate activity of (II); (h) identifying compounds (B) that alter expression of (II); and (i) (A), (B) and herbicides identified by methods (g) and (h).