发明名称 |
PROTEINS PRODUCING AN ALTERED IMMUNOGENIC RESPONSE AND METHODS OF MAKING AND USING THE SAME |
摘要 |
The present invention relates to a novel methods and compositions for producing hyper and hypo allergenic compositions. Specifically, the present invention comprises neutralizing or reducing the ability of T-cells to recognize epitopes and thus prevent sensitization of an individual to the protein. Alternatively, T-cell epitopes are mutated to produce increased immunogenic reactions.
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申请公布号 |
CA2424720(A1) |
申请公布日期 |
2002.05.23 |
申请号 |
CA20012424720 |
申请日期 |
2001.09.26 |
申请人 |
GENENCOR INTERNATIONAL, INC. |
发明人 |
ESTELL, DAVID A.;HARDING, FIONA A. |
分类号 |
G01N33/53;C12N9/56;C12N9/64;G01N33/50;G01N33/68;(IPC1-7):G01N33/549 |
主分类号 |
G01N33/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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