发明名称 Labeled complex and method of analysis therewith
摘要 <p>A labeled complex formed by combining a labeling agent with a biological substance, where the labeling agent is a trinucleus dye represented by the general formula (I)' or (II)': ring(Xa)-La-ring(Xb)-Lb-ring(Xc) (I)' [ring(Xa)-La-ring(Xb)-Lb-ring(Xc)]<(+)> Y<(-)> (II)' where the ring(Xa), ring(Xb), and ring(Xc), which mean rings having Xa, Xb, or Xc respectively, are independently a heterocyclic ring having one to three heteroatoms of oxygen, sulfur, nitrogen, or selenium, the heterocyclic ring being unsubstituted or substituted by any of a substituted or unsubstituted alkyl group, a substituted or unsubstituted aryl group, and a substituted or unsubstituted aralkyl group; La and Lb are independently a methine chain composed of one to six substituted or unsubstituted methine linkage, and one of La and Lb may be omitted to link directly the heterocyclic rings; and Y<(-)> represents an anion. A method of analysis, comprises combining any of the labeled complex with a target substance to be detected, and detecting the target substance optically.</p>
申请公布号 EP0609894(B1) 申请公布日期 2002.05.22
申请号 EP19940101720 申请日期 1994.02.04
申请人 CANON KABUSHIKI KAISHA 发明人 MIYAZAKI, TAKESHI;OKAMOTO, TADASHI;TANAKA, KAZUMI;ONISHI, TOSHIKAZU;FUKUI, TETSURO;YAMAMOTO, NOBUKO
分类号 C07D235/00;C07D277/20;C07D277/34;C07D277/36;C07D401/14;C07D403/14;C07D413/14;C07D417/06;C07D417/14;C07K14/00;C07K14/42;C07K14/575;C07K16/00;C09B23/00;C12Q1/68;G01N33/52;G01N33/533;G01N33/58;(IPC1-7):G01N33/58 主分类号 C07D235/00
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