发明名称 |
Process for the preparation of 6.alpha.-fluoro,9,11.beta.-epoxy-steroids |
摘要 |
<p>Described herein is a process for the preparation of 6 alpha -fluorosteroids of formula (I), in which R is chosen from H, OH and an alkyl group with from 1 to 4 carbon atoms and R' is a carboxyalkyl group with from 1 to 4 carbon atoms in the alkyl chain, comprising the selective fluorination at the 6 alpha -position <CHEM> by treatment of the compound of formula (III), wherein R and R' are as defined above, with an electrophilic fluorinating agent.</p> |
申请公布号 |
EP1207166(A2) |
申请公布日期 |
2002.05.22 |
申请号 |
EP20010112124 |
申请日期 |
2001.05.17 |
申请人 |
FARMABIOS S.P.A. |
发明人 |
LA LOGGIA, FILIPPO;DA COL, MARCO |
分类号 |
C07J71/00;(IPC1-7):C07J71/00 |
主分类号 |
C07J71/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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