摘要 |
The invention relates to an isolated polynucleotide comprising a polynucleotide sequence chosen from the group consisting of a) polynucleotide which is identical to the extent of at least 70% to a polynucleotide which codes for a polypeptide which comprises the amino acid sequence of SEQ ID No. 2; b) polynucleotide which codes for a polypeptide which comprises an amino acid sequence which is identical to the extent of at least 70% to the amino acid sequence of SEQ ID No. 2; c) polynucleotide which is complementary to the polynucleotides of a) or b); and a process for the fermentative preparation of nicotinic acid or nicotinic acid derivatives using coryneform bacteria in which at least the nadA gene is present in enhanced form, and the use of polynucleotides which comprise the sequences according to the invention as hybridization probes. |