发明名称 Method for treatment of allergic reaction using formyl peptide
摘要 Methods for treating allergies, cutaneous inflammation, arthritis, chronic obstruction pulmonary disease and treating chronic inflammatory bowel disease are described. Also described is a method for inhibiting the infiltration of eosinophils into airways of a patient, a method for inhibiting the mucous release into airways of a patient, a method for blocking IgE activation of a lymphocyte, a method for stabilizing the cell membrane of a lymphocyte; thereby preventing their further involvement in the increased inflammatory response to an IgE antigen challenge, and a method for inhibiting the migration of T-cells. Such methods involve administering to said patient a therapeutically effective amount of a peptide having the formula f-Met-Leu-X, wherein X is selected from the group consisting of Tyr, Tyr-Phe, Phe-Phe and Phe-Tyr.
申请公布号 US6391856(B1) 申请公布日期 2002.05.21
申请号 US19980190043 申请日期 1998.11.10
申请人 HISTATEK, LLC 发明人 HOUCK JOHN C.;CLAGETT JAMES
分类号 A61K45/00;A61K38/00;A61P11/06;A61P19/02;A61P29/00;A61P37/02;A61P43/00;C07K5/08;C07K5/083;C07K5/10;C07K5/103;C07K7/06;(IPC1-7):A61K38/07 主分类号 A61K45/00
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