| 发明名称 |
Process for preparing single enantiomer narwedine |
| 摘要 |
A process for the preparation of substantially single enantiomer (-)-narwedine comprises seeding a solution of racemic narwedine dissolved in a solvent with substantially single enantiomer (-)-narwedine, provided that if an added amine base is present the ratic solvent:added amine base is greater than 15:1.
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| 申请公布号 |
US6392038(B1) |
申请公布日期 |
2002.05.21 |
| 申请号 |
US20000402722 |
申请日期 |
2000.01.10 |
| 申请人 |
JANSSEN PHARMACEUTICA, N.V. |
发明人 |
POTTER GERARD ANDREW;TIFFIN PETER DAVID |
| 分类号 |
C07D491/048;A61K31/55;A61P25/28;C07D491/10;(IPC1-7):C07D491/10 |
主分类号 |
C07D491/048 |
| 代理机构 |
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