发明名称 Myt1 kinase inhibitors
摘要 A compound according to Formula (I), hereinbelow:wherein A represents a covalent bond, or a 1,2, 1,3 or 1,4-disubstituted aryl amine ring selected from the group consisting of: whereinR is independently selected from the group consisting of H, OMe, Cl, Br, F, NO2, and CN;n is an integer from 1 to 4;each X is independently selected from the group consisting of H, Br, CH3, NO2, CN, and NR1R2;each Ar is independently optionally substituted phenyl or an optionally substituted 5 or 6 membered heterocyclic ring comprising one or more heteroatoms selected from N, O and S; andR1 and R2 are, independently, hydrogen or C1-4 alkyl, branched or cyclic, optionally containing O or N.
申请公布号 US6391894(B1) 申请公布日期 2002.05.21
申请号 US20010857520 申请日期 2001.07.19
申请人 SMITHKLINE BEECHAM CORPORATION 发明人 LAGO MARIA A.
分类号 C07D277/20;A61K31/426;A61K31/427;A61P9/14;A61P17/06;A61P27/02;A61P29/00;A61P35/00;A61P35/02;A61P35/04;A61P43/00;C07D277/38;C07D277/42;C07D417/14;(IPC1-7):A61K31/440;C07D277/22;C07D401/02 主分类号 C07D277/20
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