发明名称 Intermediates for the preparation of N-[2-(carboxymethoxy) ethyl]-N-(carboxymethyl) glycine
摘要 Compounds represented by the formulawherein R and R1 independently represent H, -CH2CN or -CH2CO2X, with the proviso that R and R1 can not be both H or -CH2CO2X; and X represents hydrogen, an alkali metal or alkaline earth metal are disclosed. These compounds are useful as intermediate compounds in the preparation of N-[2-(carboxymethoxy)ethyl]-N-(carboxy-methyl)glycine. These intermediates can be formed by contacting 3-morpholinone with glycolonitrile under alkaline conditions to form an aminonitrile which can be hydrolyzed and contacted with additional glycolonitrile to form the nitrile intermediate which can be converted to N-[2-(carboxymethoxy)ethyl]-N-(carboxymethyl)glycine via hydrolysis.
申请公布号 US6392095(B2) 申请公布日期 2002.05.21
申请号 US20010822955 申请日期 2001.03.30
申请人 THE DOW CHEMICAL COMPANY 发明人 ATHEY PHILLIP S.;WILSON DAVID A.
分类号 C07C227/26;C07C229/12;C07C255/25;(IPC1-7):C07C229/10 主分类号 C07C227/26
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