发明名称 Conformationally restricted polyamines
摘要 Compounds of Formula I:wherein A is C2-C6 alkene, C3-C6 cycloalkyl, cycloalkenyl, or cycloaryl; B is independently a single bond, C1-C6 alkyl alkenyl; D is independently C1-C6 alkyl or alkenyl, or C3-C6 cycloalkyl, cycloalkenyl, or cycloaryl; and E is independently H, C3-C6 alkyl or alkenyl; and pharmaceutically-suitable salts thereof; a synthetic method therefor, pharmaceutical dosage forms containing one of more of these compounds, and use of these compounds in the treatment of neoplastic cell growth, are disclosed.
申请公布号 US6392098(B1) 申请公布日期 2002.05.21
申请号 US19990280278 申请日期 1999.03.29
申请人 WISCONSIN ALUMNI RESEARCH FOUNDATION 发明人 FRYDMAN BENJAMIN J.;MARTON LAURENCE J.;REDDY VENODHAR K.;VALASINAS ALDONIA L.;WITIAK DONALD T.
分类号 C07C211/18;C07C211/22;C07C211/36;(IPC1-7):A61K31/13 主分类号 C07C211/18
代理机构 代理人
主权项
地址