发明名称 |
YEAST DERIVED VACCINE AGAINST IPNV |
摘要 |
Disclosed are processes for producing a vaccine for use against infectious pancreatic necrosis virus (IPNV) in fish, which process comprises culturing a yeast host cell which expresses, and preferably secretes, an IPNV polypeptide, and formulating the polypeptide as a vaccine (preferably by using, or partially purifying) the supernatant. Such vaccines have advantages over vaccines produced in bacteria. Also disclosed are vaccines based VP3 and VP2var proteins, optionally in combination with antigens protective against other fish diseases. The invention further provides related materials (e.g. primers, vectors and host cells) and methods and uses of the vaccines for prophylaxis and therapy.
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申请公布号 |
WO0238770(A1) |
申请公布日期 |
2002.05.16 |
申请号 |
WO2001GB04986 |
申请日期 |
2001.11.12 |
申请人 |
THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN;MELVIN, WILLIAM, THOMAS;BREEMAN, SUZANNE;LABUS, MARIE, BEAGLEY |
发明人 |
MELVIN, WILLIAM, THOMAS;BREEMAN, SUZANNE;LABUS, MARIE, BEAGLEY |
分类号 |
A61P31/12;C07K14/08;C12N1/19;C12N15/40;(IPC1-7):C12N15/40;A61K39/12;C12N15/81;A61K39/39;A61K39/295 |
主分类号 |
A61P31/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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