| 摘要 |
A device for storing and mixing an injectate includes a fluid holder removably coupled to an ampoule. The fluid holder initially contains a fluid and the ampoule initially contains a dry reagent. A breakable membrane may be included between the fluid holder and ampoule to prevent the undesirable mixing of the fluid with the dry reagent. Upon application of force to a plunger rod disposed within the fluid holder, fluid is introduced into the ampoule wherein it is mixed with the dry reagent to create an injectable mixture. Air or gas present in the ampoule may be removed therefrom; the fluid holder may be decoupled from the ampoule; and the ampoule may be further coupled to a needle-less injector for administration of an injection of the mixture. The device is particularly useful for lyophilized pharmaceuticals that rapidly lose medicinal efficacy once in solution form.
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