| 摘要 |
<p>Novel amide derivatives characterized in that, in N({[4-(substituted thiazol-4-yl)phenyl]carbamoyl}methyl)amide derivatives, the N atom in the amido group carries an aryl or heteroaryl substituent (i.e., an aromatic ring group) directly attached thereto. Because of having an excellent anti-herpesviral activity, these amide derivatives are useful as drugs and antiviral agents, in particular, preventives or remedies for various diseases caused by the infection with herpesviruses, more specifically, various herpesvirus infections such as pox (blister) caused by the infection with varicella zoster virus, herpes zoster caused by the recurrent infection with latent varicella zoster virus, herpes labialis and herpes encephalitis caused by the infection with HSV-1 and genital herpes caused by the infection with HSV-2.</p> |
