发明名称 |
CHIMERIC MOLECULES TO MODULATE GENE EXPRESSION |
摘要 |
The present invention provides a chimeric molecule including a base-pairing segment that binds specifically to a single-stranded nucleic acid molecule; and a moiety that modulates splicing or translation. The invention also provides a chimeric molecule including a base-pairing segment that binds specifically to a double-stranded nucleic acid molecule; and a peptide that modulates transcription, wherein the peptide comprises up to about one hundr ed amino acid residues. |
申请公布号 |
CA2437942(A1) |
申请公布日期 |
2002.05.16 |
申请号 |
CA20012437942 |
申请日期 |
2001.11.09 |
申请人 |
COLD SPRING HARBOR LABORATORY |
发明人 |
CARTEGNI, LUCA;KRAINER, ADRIAN R. |
分类号 |
A61K38/00;A61K48/00;C12N15/113;(IPC1-7):C07K17/10;C07K17/02;C12N15/63 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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