| 发明名称 |
MODULATORS OF BRUTON'S TYROSINE KINASE AND BRUTON'S TYROSINE KINASE INTERMEDIATES AND METHODS FOR THEIR IDENTIFICATION AND USE IN THE TREATMENT AND PREVENTION OF OSTEOPOROSIS AND RELATED DISEASE STATES |
| 摘要 |
The present invention relates to the identification of Bruton's Tyrosine Kinase as a critical intermediate in the process of osteoclst activation, modulators. It is now found that such modulators are useful in the treatment and prevention of osteoporosis and related disease states. |
| 申请公布号 |
WO0238797(A2) |
申请公布日期 |
2002.05.16 |
| 申请号 |
WO2001US51415 |
申请日期 |
2001.10.22 |
| 申请人 |
BRISTOL-MYERS SQUIBB COMPANY;MCATEE, PATRICK |
发明人 |
MCATEE, PATRICK |
| 分类号 |
G01N33/50;A61K38/45;A61K45/00;A61K48/00;A61P19/10;A61P43/00;C12N5/06;C12N9/00;C12N9/99;C12Q1/02;C12Q1/48;G01N33/15;G01N33/573 |
主分类号 |
G01N33/50 |
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