发明名称 |
<i>GRIDLOCK</i> NUCLEIC ACID MOLECULES, POLYPEPTIDES, AND DIAGNOSTIC AND THERAPEUTIC METHODS |
摘要 |
The invention provides a novel gene, <i>gridlock</i>, and its encoded protein. <i>gridlock</i> plays a role in vascular development and modeling, and a mutation in <i>gridlock</i> has been associated with an aortic arch disease, coarctation. Thus, <i>gridlock</i> nucleic acid molecules and polypeptides can be used in methods of diagnosing, treating, and preventing <i>gridlock</i>-related diseases and conditions, such as aortic arch diseases.
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申请公布号 |
WO0134636(A9) |
申请公布日期 |
2002.05.16 |
申请号 |
WO2000US30439 |
申请日期 |
2000.11.03 |
申请人 |
THE GENERAL HOSPITAL CORPORATION |
发明人 |
FISHMAN, MARK, C.;ZHONG, TAO |
分类号 |
A01K67/027;A61K31/7088;A61K35/12;A61K35/76;A61K38/00;A61K39/395;A61K48/00;A61P9/00;A61P9/10;C07K14/47;C07K16/18;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/09;C12Q1/68;G01N33/15;G01N33/50;G01N33/53;G01N33/566;(IPC1-7):C07K1/00;C07H21/04;A01N43/04 |
主分类号 |
A01K67/027 |
代理机构 |
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