| 发明名称 |
HYDROLYTICALLY UNSTABLE COMPOSITIONS |
| 摘要 |
The present invention relates to a new stable oral pharmaceutical formulation comprising: a) a nucleus formed by a core; b) a first layer that comprises a polymer coating sealing the core and optionally one or more hydrophobic excipients; and c) a second layer coating the first layer, wherein said second layer comprises one or more labile pharmaceutically active compounds in one or more acceptable hydrophobic excipients. |
| 申请公布号 |
WO0238133(A2) |
申请公布日期 |
2002.05.16 |
| 申请号 |
WO2001EP12714 |
申请日期 |
2001.11.02 |
| 申请人 |
F. HOFFMAN-LA ROCHE AG |
发明人 |
ODINK, DEBRA, ALIDA;SUE, I-LAN;VISOR, GARY, CONARD |
| 分类号 |
A61K47/30;A61K9/16;A61K9/20;A61K9/30;A61K9/48;A61K9/50;A61K31/4164;A61K31/4168;A61K31/4174;A61K45/00;A61K47/32;A61K47/46;A61P13/02 |
主分类号 |
A61K47/30 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
