发明名称 |
Methods and compositions for identifying a polynucleotide encoding a protease |
摘要 |
Methods are disclosed whereby protease activity is directly linked to delivery of a transferable label to a target cell which expresses a protease, via fusion of viral display packages comprising the transferable label with the target cell. The methods can be used, inter alia, to identify proteases, including previously undiscovered proteases or variants of known proteases which may have altered substrate specificity.
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申请公布号 |
US6387686(B2) |
申请公布日期 |
2002.05.14 |
申请号 |
US20010791427 |
申请日期 |
2001.02.23 |
申请人 |
BIOFOCUS DISCOVERY LIMITED |
发明人 |
CHADWICK MARK P.;RUSSELL STEPHEN J.;BUCHHOLZ CHRISTIAN |
分类号 |
A61K38/00;C07K14/15;C07K14/705;C12N9/64;C12N15/10;C40B40/02;(IPC1-7):C12N7/00;C12Q1/70;C12Q1/68;C07H21/04 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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