THREE-DIMENSIONAL SKIN MODEL

摘要

The invention relates to methods for cultivating dermal fibroblasts, methods for producing in vitro dermis equivalents, methods for producing three-dimensional in vitro skin equivalents, an in vitro dermis equivalent, a three-dimensional in vitro skin equivalent and methods for determining the effect of a chemical substances or an agent on human skin cells using the in vitro dermis equivalent and/or the in vitro skin equivalent.