发明名称 |
AMIDINO-UREA SEROTONIN RECEPTOR LIGANDS AND COMPOSITIONS, THEIR PHARMACEUTICAL USES, AND METHODS FOR THEIR SNYTHESIS |
摘要 |
Novel amidino-urea 5-HT7 receptor ligands, methods of preparing such ligands , intermediate compounds useful in the preparation of the receptor ligands, pharmaceutical compositions comprising the receptor ligands, and methods of treating sleep disorders, pain, depression, and schizophrenia employing the receptor ligands are disclosed. The receptor ligands have formula (1): where in the formula variables are as defined herein, and pharmaceutically acceptable salts, solvates, active metabolites, or prodrugs thereof.
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申请公布号 |
CA2425285(A1) |
申请公布日期 |
2002.05.10 |
申请号 |
CA20012425285 |
申请日期 |
2001.10.26 |
申请人 |
WARNER-LAMBERT COMPANY LLC |
发明人 |
HONG, YUFENG;LUTHIN, DAVID ROBERT;PENG, ZHENGWEI;TOMPKINS, EILEEN VALENZUELA;KUKI, ATSUO |
分类号 |
C07D295/20;A61K31/175;A61K31/381;A61K31/40;A61K31/4045;A61K31/4164;A61K31/437;A61K31/4402;A61K31/4406;A61K31/445;A61K31/4465;A61K31/4468;A61K31/4525;A61K31/454;A61K31/472;A61K31/495;A61P25/04;A61P25/18;A61P25/20;A61P25/24;A61P43/00;C07C279/22;C07C279/24;C07C323/48;C07D207/09;C07D209/14;C07D209/16;C07D211/16;C07D211/26;C07D211/58;C07D211/60;C07D211/62;C07D213/36;C07D213/40;C07D217/06;C07D233/61;C07D233/64;C07D235/30;C07D295/215;C07D333/20;C07D405/06;C07D413/06;C07D471/10;C07D521/00;(IPC1-7):C07C279/24;A61K31/155 |
主分类号 |
C07D295/20 |
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