DELIVERY SYSTEM FOR ENTRAPPING CHARGED MACROMOLECULES AND A METHOD FOR PREPARING SAME
摘要
The present invention relates to a new delivery system and method for producing same. The delivery system is a biphasic system of delivering charged macromolecules and comprises a negatively charged hydrophobic organic phase and a positively charged inorganic phase. The organic phase and the inorganic phase entrapping added macromolecules. The macromolecules are entrapped by electrostatic bonds between the organic phase, the inorganic phase and the macromolecules. The method for producing the delivery system comprises the steps of contacting together and mixing a negatively charged organic phase, a charged macro-molecule and positively charged inorganic phase.
申请公布号
WO0236097(A2)
申请公布日期
2002.05.10
申请号
WO2001CA01535
申请日期
2001.10.30
申请人
LES LABORATOIRES BIO-MED INC.;ELAZHARY, YOUSSEF;MAKABI-PANZU, BOBY;HURLEY, DAVID, JOHN;LAURENT, SYLVETTE