发明名称 CHOLESTEROL LOWERING BENZO`B! THIOPHENES AND BENZO`D! ISOTHIAZOLES
摘要 The present invention relates to compounds of formula (I) wherein U, A<1>, A<2>, A<3>, A<4>, V, X, Y, Z, Q, m and n are as defined in the description and claims and pharmaceutically acceptable salts and/or pharmaceutically acceptable esters thereof. The compounds are useful for the treatment and/or prophylaxis of diseases which are associated with 2,3-oxidosqualene-lanosterol cyclase such as hypercholesterolemia, hyperlipemia, arteriosclerosis, vascular diseases, mycoses, gallstones, tumors and/or hyperproliferative disorders, and treatment and/or prophylaxis of impaired glucose tolerance and diabetes.
申请公布号 WO0236584(A1) 申请公布日期 2002.05.10
申请号 WO2001EP12451 申请日期 2001.10.26
申请人 F. HOFFMANN-LA ROCHE AG 发明人 AEBI, JOHANNES;ACKERMANN, JEAN;DEHMLOW, HENRIETTA;MAERKI, HANS-PETER;MORAND, OLIVIER
分类号 A61K31/381;A61K31/397;A61K31/428;A61K31/454;A61K31/496;A61K31/506;A61K31/5377;A61P3/00;A61P3/06;A61P3/10;A61P9/00;A61P9/10;A61P13/12;A61P31/10;A61P33/00;A61P35/00;C07D275/04;C07D275/06;C07D333/54;C07D409/12;C07D417/12;C07D521/00;(IPC1-7):C07D333/54 主分类号 A61K31/381
代理机构 代理人
主权项
地址