METHOD FOR OBTAINING ANTIGENIC STRUCTURES ENHANCING SPECIFIC CROSS REACTIVITY

摘要

The invention relates to a method for obtaining high cross reactivity antigenic structures that are capable of enhancing an immune response to peptidic antigens administered systemically and/or mucosally and to the chemical structures obtained with said method and the formulations obtained from said structures and their utilization. The method describes the obtention of new dendrimeric structures from the selection and synthesis of dendrimers that are subsequently coupled to carrier molecules. The resulting structures can be used conveniently adjuvated or in a formulation in which several antigens of this type can be introduced, a synergistic effect taking place between these components in relation to the cross reactivity and the immunogenicity of the response obtained. The preparation may also contain stabilizers and preserving agents. The resulting antigenic structures can be used in the pharmaceutical industry as vaccine formulations for human and veterinary use and as part of diagnostic systems.