| 发明名称 |
PGD2 RECEPTOR ANTAGONISTIC PHARMACEUTICAL COMPOSITIONS |
| 摘要 |
Compounds of the general formula (I) which are metabolically stable and exhibit PGD2 receptor antagonism, wherein Y is a bicyclic ring; R<1> is optionally substituted heteroaryl; R<2> is hydrogen or the like; R<3> is -CH2-CH2-CH2-CH2-CH=CH-COOR<4>,- CH2-CH2-CH2-CH2-X<1>-CH2-COOR<4>, -CH2-CH=CH-CH2-X<1>-CH2-COOR<4>, or -CH2-CH2-CH2-CH2-COOR<4>; R<4> is hydrogen or the like; and X<1> is -O- or the like.
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| 申请公布号 |
WO0236583(A1) |
申请公布日期 |
2002.05.10 |
| 申请号 |
WO2001JP09435 |
申请日期 |
2001.10.26 |
| 申请人 |
SHIONOGI & CO., LTD.;TANIMOTO, NORIHIKO;HIRAMATSU, YOSHIHARU;HONMA, TSUNETOSHI;INAGAKI, MASANAO |
发明人 |
TANIMOTO, NORIHIKO;HIRAMATSU, YOSHIHARU;HONMA, TSUNETOSHI;INAGAKI, MASANAO |
| 分类号 |
C07D307/79;C07D307/85;C07D333/38;C07D333/54;C07D333/64;C07D333/70;C07D333/76;C07D495/04;(IPC1-7):C07D333/38;C07D333/68;C07D333/62;C07D337/14;C07D307/68;C07D307/84;C07D307/86;C07D307/91;C07D207/34;C07D209/42;C07D333/74;A61K31/381;A61K31/38;A61K31/341 |
主分类号 |
C07D307/79 |
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