发明名称 |
Anaerobic bacterium as a drug for cancer gene therapy |
摘要 |
The present invention provides a bacterium belonging to the genus Bifidobacterium, by which DNA coding for a protein having an antitumor activity or DNA coding for a protein having the activity of converting a precursor of an antitumor substance into the antitumor substance is delivered to tumor tissues specifically under anaerobic conditions thereby expressing the protein encoded by the DNA, as well as a pharmaceutical composition comprising said anaerobic bacterium.
|
申请公布号 |
US2002054865(A1) |
申请公布日期 |
2002.05.09 |
申请号 |
US20010816391 |
申请日期 |
2001.03.26 |
申请人 |
FUJIMORI MINORU;TANIGUCHI SHUN?APOS,ICHIRO;AMANO JUN;YAZAWA KAZUYUKI;KANO YASUNOBU;NAKAMURA TOSHIYUKI;SASAKI TAKAYUKI |
发明人 |
FUJIMORI MINORU;TANIGUCHI SHUN?APOS,ICHIRO;AMANO JUN;YAZAWA KAZUYUKI;KANO YASUNOBU;NAKAMURA TOSHIYUKI;SASAKI TAKAYUKI |
分类号 |
A61K48/00;C07K14/195;(IPC1-7):A61K48/00;C12N15/03;C12N1/21 |
主分类号 |
A61K48/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|