| 发明名称 |
N-acylsulfonamide apoptosis promoters |
| 摘要 |
N-Benzoyl arylsulfonamides having the formula are BCL-Xl inhibitors and are useful for promoting apoptosis. Also disclosed are BCL-Xl inhibiting compositions and methods of promoting apoptosis in a mammal.
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| 申请公布号 |
US2002055631(A1) |
申请公布日期 |
2002.05.09 |
| 申请号 |
US20010935581 |
申请日期 |
2001.08.24 |
| 申请人 |
AUGERI DAVID J.;BAUMEISTER STEVEN A.;BRUNCKO MILAN;DICKMAN DANIEL A.;DING HONG;DINGES JURGEN;FESIK STEPHEN W.;HAJDUK PHILIP J.;KUNZER AARON R.;MCCLELLAN WILLIAM;NETTESHEIM DAVID G.;OOST THORSTEN;PETROS ANDREW M.;ROSENBERG SAUL H.;SHEN WANG;THOMAS SHEELA A.;WANG XILU;WENDT MICHAEL D. |
发明人 |
AUGERI DAVID J.;BAUMEISTER STEVEN A.;BRUNCKO MILAN;DICKMAN DANIEL A.;DING HONG;DINGES JURGEN;FESIK STEPHEN W.;HAJDUK PHILIP J.;KUNZER AARON R.;MCCLELLAN WILLIAM;NETTESHEIM DAVID G.;OOST THORSTEN;PETROS ANDREW M.;ROSENBERG SAUL H.;SHEN WANG;THOMAS SHEELA A.;WANG XILU;WENDT MICHAEL D. |
| 分类号 |
C07C311/51;C07C317/28;C07C323/12;C07C323/17;C07C323/25;C07C323/30;C07C323/37;C07C323/58;C07C323/60;C07D203/10;C07D205/12;C07D207/24;C07D207/40;C07D207/404;C07D209/08;C07D209/96;C07D211/44;C07D211/70;C07D211/74;C07D213/61;C07D213/70;C07D213/71;C07D215/14;C07D215/22;C07D215/227;C07D215/48;C07D217/04;C07D221/20;C07D231/12;C07D235/08;C07D235/26;C07D241/16;C07D249/04;C07D263/56;C07D263/58;C07D277/62;C07D277/64;C07D295/13;C07D295/155;C07D295/185;C07D295/205;C07D295/215;C07D295/26;C07D307/14;C07D317/54;C07D333/28;C07D333/68;C07D401/06;C07D401/12;C07D405/04;C07D417/12;C07D451/02;(IPC1-7):C07D417/02;C07D413/02;C0743/02;C0741/02 |
主分类号 |
C07C311/51 |
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