发明名称 |
XANTHAN-ESTER AND ACRIDAN SUBSTRATES FOR HORSERADISH PEROXIDASE |
摘要 |
Xanthan esters and acridans are substrates for horseradish peroxidase. These stable, enzymatically cleavable chemiluminescent esters are substrates for horseradish peroxidase which, together with peroxide is among the extensively used enzyme in enzyme-linked detection methods, including immunoassays, oligonucleotide detection and nucleic acid hybridization. The novel compounds are used, together with peroxide, alkali and the peroxidase, to indicate the presence and/or concentration of target compounds. The assays may be enhanced by the use of polymeric quaternary onium enhancement compounds or similar compounds selected to enhance the chemiluminescence emitted. |
申请公布号 |
EP1119554(A4) |
申请公布日期 |
2002.05.08 |
申请号 |
EP19990948157 |
申请日期 |
1999.09.10 |
申请人 |
TROPIX, INC. |
发明人 |
BRONSTEIN, IRENA;EDWARDS, BROOKS;VOYTA, JOHN, C.;JUO, ROUH-RONG |
分类号 |
G01N33/53;C07D219/06;C07D311/84;C09K11/07;C12Q1/28;G01N21/76;G01N33/535;G01N33/577 |
主分类号 |
G01N33/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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