发明名称 |
Stable amorphous amifostine compositions and dosage form |
摘要 |
The present invention relates to a sterile, stable dosage forms suitable for reconstitution and parenteral administration to a patient, said dosage form comprising an amorphous aminoalkyl dihydrogen phosphorothioate, and of amifostine in particular. The invention further relates to a method of preparing such a dosage form, which typically exhibits enhanced thermal stability as compared to existing vacuum dried amorphous amifostine.
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申请公布号 |
US6384259(B1) |
申请公布日期 |
2002.05.07 |
申请号 |
US19990440650 |
申请日期 |
1999.11.16 |
申请人 |
MEDIMMUNE ONCOLOGY, INC. |
发明人 |
STOGNIEW MARTIN;ZADEI JAVAD M. |
分类号 |
A61K9/08;A61C8/00;A61K9/14;A61K9/19;A61K31/66;A61K31/661;A61K47/04;A61K47/10;A61K47/12;A61K47/18;A61K47/22;A61K47/26;A61K47/28;A61K47/32;A61K47/38;A61K47/42;A61P7/00;A61P13/12;A61P31/18;A61P35/00;A61P39/00;A61P43/00;(IPC1-7):C07F9/02;A01N43/42;A61K31/47 |
主分类号 |
A61K9/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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