发明名称 3-bicycloaryl-2-aminomethyl bicycloalkanes as serotonine reuptake inhibitors
摘要 A pharmaceutical compound of formula (I) in which R1 and R2 are each hydrogen or C1-4 alkyl, or R1 and R2 together with the nitrogen atom to which they are attached form an azetidinyl, pyrrolidinyl, piperidinyl, piperazinyl, or morpholino group, said group being optionally substituted with 1 to 3 C1-4alkyl substituents, R3 is a naphythyl, indolyl, benzothienyl, benzofuranyl, benzothiazolyl, quinolinyl or isoquinolinyl group, said group being optionally substituted, and n is 1 or 2; or a salt or ester thereof.
申请公布号 US6384281(B1) 申请公布日期 2002.05.07
申请号 US20010958218 申请日期 2001.10.03
申请人 ELI LILLY AND COMPANY 发明人 KEENAN MARTINE;MILUTINOVIC SANDRA GINETTE;TUPPER DAVID EDWARD
分类号 C07D333/54;A61K31/13;A61K31/16;A61K31/381;A61K31/4025;A61K31/404;A61P1/04;A61P1/08;A61P3/04;A61P9/04;A61P9/12;A61P15/10;A61P25/00;A61P25/04;A61P25/06;A61P25/16;A61P25/18;A61P25/20;A61P25/22;A61P25/24;A61P25/28;A61P25/32;A61P25/34;A61P25/36;C07C211/30;C07C215/64;C07C217/74;C07C233/58;C07D209/08;C07D209/14;C07D209/18;C07D333/58;C07D333/60;C07D333/62;(IPC1-7):A61K31/44 主分类号 C07D333/54
代理机构 代理人
主权项
地址