发明名称 |
Human oxalyl-CoA Decarboxylase |
摘要 |
A human oxalyl-CoA decarboxylase polypeptide and DNA(RNA) encoding such polypeptide and a procedure for producing such polypeptide by recombinant techniques and for producing an antibody against such polypeptide are disclosed. Also disclosed is a combination of the polypeptide of the present invention and a suitable pharmaceutical carrier for providing a therapeutically effective amount of the polypeptide for the treatment of urolithiasis and hyperoxaluria. Also disclosed are assays for identifying mutations in nucleic acid sequence encoding a polypeptide of the present invention and for detecting altered levels of the polypeptide of the present invention.
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申请公布号 |
US6383737(B2) |
申请公布日期 |
2002.05.07 |
申请号 |
US20000732020 |
申请日期 |
2000.12.08 |
申请人 |
HUMAN GENOME SCIENCES, INC. |
发明人 |
OLSEN HENRIK S.;COLEMAN TIMOTHY A.;ADAMS MARK D. |
分类号 |
A61K38/00;C12N9/88;C12N15/60;C12Q1/68;(IPC1-7):C12Q1/527;C07K16/40 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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