| 发明名称 |
PRODUCTION METHOD OF 2-CYCLOHEXYL-2-HYDROXY-2-PHENYLACETIC ACID, INTERMEDIATE THEREFOR AND PRODUCTION METHOD THEREOF |
| 摘要 |
The present invention relates to production of 2- cyclohexyl-2-hydroxy-2-phenylacetic acid useful as an intermediate for pharmaceutical products, by an industrial means, economically, safely in a good yield. Novel 2-(2'- cyclohexen-1'-yl)-2-hydroxy-2-phenylacetic acid ester obtained by reacting cyclohexene and benzoylformic acid ester in the presence of a Lewis acid is hydrolyzed and reduced to give 2- cyclohexyl-2-hydroxy-2-phenylacetic acid.
|
| 申请公布号 |
CA2361156(A1) |
申请公布日期 |
2002.05.07 |
| 申请号 |
CA20012361156 |
申请日期 |
2001.11.06 |
| 申请人 |
SUMIKA FINE CHEMICALS CO., LTD. |
发明人 |
GAO, WEI-GUO;IGI, MASAMI;TAKEDA, MITSUHIRO;IKEMOTO, TETSUYA |
| 分类号 |
C07C51/09;C07C51/36;C07C67/303;C07C67/343;C07C69/732;(IPC1-7):C07C65/01;C07C51/00 |
主分类号 |
C07C51/09 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
